Fig 1: MC degranulation markers in patient serum are increased relative to clinical severity of patients post-SARS-CoV-2 infection. The presence of (A) CMA1, (B) CPA3 and (C) TPSB2 in patient serum was determined by ELISA. Healthy controls (n=17) were used to compare to patients post-SARS-CoV-2 infection with moderate (admission to hospital; n=30), or severe (admission to ICU; n=30) clinical outcome. Statistical significance was determined using a one-way ANOVA with Kruskal-Wallis multiple comparison test. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.